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KMID : 0359320000400030563
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Korean Journal of Veterinary Research
2000 Volume.40 No. 3 p.563 ~ p.573
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Evaluation of the recent live vaccination effects against Newcastle disease under field conditions
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강경수/Kang, Kyung Soo
김재학/한명국/성환우/이중복/송창선/이윤정/Kim, Jae Hak/Han, Myung Guk/Seong, Hwan Woo/Lee, Joong Bok/Song, Chang Seon/Lee, Youn Jeong
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Abstract
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Periodic outbreaks of Newcastle disease (ND) caused by velogenic viscerotropic ND virus (vvNDV) has become a major concern in Korea nowadays. Throughout last epidemic, the winter season in 2000, most chicken flocks infected early, under 2-4 weeks of age, showed high mortality up to 50-100%. Serum samples collected from 201 breeder, 284 layer and 112 broiler chicken flocks were examined to evaluate the efficacy of various vaccination methods and programs routinely used for mass vaccination in the field poultry farms. Despite repeated live vaccination, most poultry flocks vaccinated by drinking water route using nipple water supply system failed to produce solid active immune response to NDV during the growing time.
In the present study, we applied the spray vaccination technique using Ulvavac or Desvac sprayer to the experimental poultry flocks and examined the efficacy of live vaccination effects induced by it under field condition. Measurable antibody to NDV as well as early protection against vvNDV challenge were found in poultry flocks vaccinated by spray route. Further, we did not found significant post vaccination reactions caused by spray vaccination if properly administered. These data indicate that the spray vaccination will be safe and reliable mass vaccination method for the prevention of ND.
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